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Evidence-Based Ingredients

Science-led. Individually prescribed.

The ingredients below illustrate examples of evidence-based pathways that may be selected within an individually compounded formulation following clinical assessment by one of our UK registered prescribers.

Nitric oxide pathway

L-Arginine

Nitric oxide precursor

L-Arginine is an amino acid involved in the production of nitric oxide, a signalling molecule associated with vascular relaxation and localized blood flow.

Nitric oxide Blood flow Vascular support
Neurovascular support

Ergoloid Mesylates

Microvascular support

Ergoloid mesylates may be selected within a compounded formulation where support for local microcirculation and neurovascular response is clinically appropriate.

Microcirculation Vascular tone Tissue perfusion
Tissue perfusion

Pentoxifylline

Healthy tissue perfusion

Pentoxifylline is associated with effects on blood rheology and may be considered where improved local tissue perfusion forms part of the prescribed treatment rationale.

Perfusion Microcirculation Blood rheology
PDE5 pathway

Sildenafil

PDE5 inhibition

Sildenafil is a phosphodiesterase type 5 inhibitor associated with enhanced nitric oxide signalling and increased local vascular response.

PDE5 Nitric oxide Local response
Smooth muscle pathway

Aminophylline

Smooth muscle relaxation

Aminophylline is a methylxanthine derivative that may be selected within a tailored formulation where smooth muscle and local vascular pathways are clinically relevant.

Smooth muscle Methylxanthine Vascular pathway

Treatment

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